Their DL will be really good, that's my #1 concern. They have a stud from Kentucky who'd probably be our best interior DL, and let's be honest, if we had year 2 5-start Justin Scott, we'd all be amped about him being part of the rotation if not starting out right.
Our OL will be tested to the max given how banged up they are (Jagusah out, Craig back from serious injury, Absher apparently missing some practice, Lambert back from serious injury). Add in road game and brand new QB, you have serious concern about this matchup IMO.
Even though they have a likely NFL QB and stud OL, I'm not too worried about our defense.