I think you can make that argument for just about anything in medicine. I think it comes down to acceptable risk tolerance, what you have as your level and what I have as mine are going to be different. The rate at which actual hormone and more invasive treatment happens is already at a trivial level. So, for me as long as the process is being regulated (big one), conducted by health professionals, and has consent of all three parties (patient/parent/doctor) then I don't see how I would know better than all three of those aspects.