My family owns three businesses. My great-grandfather founded a road construction company in 1912, which we operate to this day. My sister founded an organic farm in 2008, which again is still operational. Small businesses, but huge regulations. It's not even that regulations are inherent nonsensical, it's the amount and the different departments running around like fools.
My great-aunt had an orchard for fifty-some years across the field, until about 2002 when the state said that if you're going to sell apple cider that it must be pasteurized. Well, such a machine cost ~$250,000. So what did she (and many other small operations) do? Closed up shop and/or retired and plowed the trees under and sold the land. Two years later, the state changed the law but the damage was done and huge corporate farms increased their marketshare.
Granted, that is a tiny instance. But people can go on and on with small stories, and they add up. Big corporations use laws to "protect people," but also/really to
increase the cost of entering the marketplace, which helps protect them.
For instance my sister sells field-raised/organic chickens, but the only chicken slaughterhouse is wayyyyy over in Holgate (hours away), so the ability for small-scale NW Ohio farmers to enter the market is harder--designed by law.
It's all a damn game, and big companies are winning big time. Regulations are, more times than not, drawn up via lobbyists from huge corporations with laws in mind that fit their model.