Since we are talking about Yuengling I will lend my knowledge to this. I live in Frackville, PA which is 10 minutes from Pottsville, PA where Yuengling originates and is brewed. It is America's oldest brewery, as the company continued to stay in business and produce near beer during Prohibition. We are located in Schuylkill County in the heart of the Pennsylvania Coal Region. This is the Northeastern and Central PA region. We are about 2 hours north of Philly.
The day Prohibition ended Mr. Yuengling had a case of his beer shipped to the White House for President Roosevelt to enjoy. The company is still based in Pottsville where they operate the original brewery along with another brewery in Port Carbon, about 5 minutes away. They currently own a brewery as well in Tampa, FL. Yuengling is available all along the eastern seaboard, not sure about all of New England though, and as far west as Ohio, and I believe Tennessee. Some bars will attempt to pass off Yuengling as an import and sell at a higher price, but don't let them fool you.
The tour is also a great experience, plus it's free and you can sample some at the end. Our region is in desperate need for tourism and we have some historical significance, so visitors are always welcome. Pottsville, Jim Thorpe (Yes the town is named after the athlete, originally it was called Mauch Chunk), Scranton, Hazleton, Etc. would all benefit from expanded tourism.